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. 2017 Jun 12;8:666. doi: 10.3389/fimmu.2017.00666

Figure 1.

Figure 1

Effect of crude protein extracts from Hericium erinaceus on trinitrobenzenesulfonic acid solution (TNBS)-induced inflammatory bowel disease (IBD) rats. (A) The technical route of this study; (B) the fresh fruiting bodies of H. erinaceus and the protein electrophoresis; (C) the hematoxylin and eosin-staining and immunohistochemistry results; (D) the Disease Activity Index scores (calculated according to the weight loss, stool consistency, and blood in feces) and observation of colons of the TNBS-induced IBD rats. Control is the normal group without any treatments, Model is the TNBS-induced IBD rats, HEP is the crude protein extract-treated group after TNBS enema, and 5-aminosalicylic acid (5-ASA) is the positive control group treated with 100 mg/(kg ⋅ day) of 5-ASA after TNBS enema. Values were expressed as means ± SDs. #P < 0.05 vs the control group, *P < 0.05, **P < 0.01 vs the model group, indicating significant differences compared with the model group.