Table 1.
Disease enrichment of p140Cap related proteins.
| TERM.ID | Term | Annotated | Significant | Expected | classicFisher | elimFisher |
|---|---|---|---|---|---|---|
| DOID:5419 | Schizophrenia | 1600 | 65 | 30.54 | 2.1E-09 | 2.1E-09 |
| DOID:12849 | ASD | 338 | 20 | 6.45 | 7.9E-06 | 7.9E-06 |
| DOID:3312 | Bipolar disorder | 981 | 37 | 18.72 | 5.3E-05 | 5.3E-05 |
| DOID:1059 | Intellectual disability | 490 | 20 | 9.35 | 1.18E-03 | 1.18E-03 |
| DOID:1826 | Epilepsy | 331 | 15 | 6.32 | 1.78E-03 | 1.78E-03 |
The table shows the 5 top terms for the TopGo disease enrichment with results from Fisher and elimFisher tests. The agreement among the orders of magnitude for both methods indicates the strong over-representation of respective disease genes among the p140Cap interacting proteins.