Table 3.
Distribution of SNPs in some target genes of antimalarial drugs and immunity
| Gene Name | Chromosome | Position | Number of SNPs |
|---|---|---|---|
| UBP1 | 1 | 190,269–210,230 | 4 |
| LSA3 | 2 | 796,752–801,568 | 6 |
| PFDHR | 4 | 748,088–749,914 | 13 |
| PFMDR1 | 5 | 957,890–962,149 | 8 |
| PFCRT | 7 | 403,222–406,317 | 5 |
| PFDHPS | 8 | 548,200–550,616 | 7 |
| MSP1 | 9 | 1,201,812–1,206,974 | 6 |
| GDV1 | 9 | 1,377,953–1,379,752 | 4 |
| MSP3 | 10 | 1,404,195–1,405,259 | 5 |
| LSA1 | 10 | 1,436,316–1,439,804 | 5 |
| PFMDR5 | 13 | 1,598,401–1,601,178 | 10 |
Abbreviations: UBP1 ubiquitinating emzyme gene, CRT chloroquine resistant transporter, MDR multidrug resistant transporter, DHFR dihydrofolate reductase, DHPS dihydropteroate synthase, GDV gametocyte development, MSP merozoite surface protein, LSA liver stage antigen