Table 3.

Measures describing how well blood cultures and SeptiFast polymerase chain reaction analyses capture the true presence or absence of disease, as related to gold standard, with 95% confidence interval

	Test
% (95% CI)	SF	BC	P value
ROP	13.2% (6.7%–17.8%)	7.3% (2.8%–17.8%)	0.322
Sensitivity	85.7% (48.6%–97.5%)	42.9% (10.2%–83.2%)	0.250
Specificity	96.9% (87.9%–99.3%)	96.9% (88.6%–99.2%)	1.000
PPV	74.7% (36.0%–93.9%)	60.2% (18.5%–90.1%)	0.255
NPV	98.4% (89.3%–99.8%)	87.0% (86.2%–94.1%)	0.105

SF SeptiFast polymerase chain reaction analysis, BC blood culture, ROP rate of positivity, PPV positive predictive value, NPV negative predictive value

P value: Two-sided P value of the null hypothesis of equal ROP, sensitivity, specificity, PPV, and NPV of SF and BC

Sensitivity: P (Test = positive | gold standard = positive)

Specificity: P (Test = negative | gold standard = negative)

PPV: P (gold standard = positive | Test = positive)

NPV: P (gold standard = negative | Test = negative)

ROP: P (Test = positive)