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. 2017 Jun 22;5(12):e13313. doi: 10.14814/phy2.13313

Figure 3.

Figure 3

EC‐MR does not regulate endothelial cell adhesion molecule expression, CD4 +  T cell and CD11b myeloid cell recruitment in response to TAC. (A) ICAM‐1 and (B) VCAM‐1 mRNA levels represented as fold versus respective Sham. Statistics, unpaired Mann–Whitney t‐test. (C) LV CD4 +  T lymphocyte recruitment, (D) CD11b+ myeloid cell and (E) Gr1 +  neutrophil recruitment determined by IHC as number of positive cells per section. Arrows indicate representative staining. Quantification of infiltrated cells is shown on the left and representative 40 ×  pictures are shown on the right. Scale bar 25 μm. n = 5 EC‐MR +/+ Sham, 8 EC‐MR +/+ TAC, 3 EC‐MR −/− Sham, 8 EC‐MR −/− TAC. Statistics D'Agostino & Pearson normality test, followed by unpaired Student's t‐test.