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. 2005 Mar;49(3):1106–1112. doi: 10.1128/AAC.49.3.1106-1112.2005

TABLE 2.

Summary of gatifloxacin pharmacokinetics following a 10-mg/kg dose of suspension and tablet formulations to children 6 to 16 years of agea

Formulation Mean (% CV) age (yr) [n] Geometric mean (% CV) AUC (μg · h/ml) [n] Geometric mean (% CV) Cmax (μg/ml) [n] Median (% CV) Tmax (h) [n] Mean (% CV) CLT/F (ml/min/kg) [n] Mean (% CV) % UR [n]
Suspension 11.0 (30) [16] 38.6 (34) [16] 3.76 (21) [16] 3.0 (52) [16] 4.52 (32) [16] 69 (27) [12]
Tablet 12.2 (28) [12] 43.7 (24) [12] 5.29 (22) [12] 1.3 (64) [12] 3.88 (25) [12] 68 (15) [6]
a

CV, coefficient of variation; % UR is the percentage of the dose recovered in urine.