TABLE 3.
Compound and parameter | P388 (mouse monocyte) | THP-1 (human monocyte) | U937 (human macrophage) | CHO (hamster ovary) | HUH7 (human hepatocyte) |
---|---|---|---|---|---|
Cycloheximide | |||||
EC50 (μg/ml) | 0.06 | 0.11 | 0.28 | 3.59 | 0.08 |
NOEC (μg/ml) | <0.1 | <0.1 | <0.1 | 1.0 | <0.1 |
Compound 1 | |||||
EC50 (μg/ml) | >100 | >100 | >100 | >100 | >100 |
NOEC (μg/ml) | 31.6 | 31.6 | 31.6 | >100 | >100 |
Trovafloxacin | |||||
EC50 (μg/ml) | 7.55 | 24.29 | 5.42 | 23.84 | 24.29 |
NOEC (μg/ml) | 1.0 | 3.16 | 1.0 | 1.0 | 3.16 |