Fig. 2.

Expression of stemness factors in BTICs is reduced by CK2 inhibition. a X456 cells were assessed for Sox2 expression after 4–24 h culture with CX-4945 (10 μM) or vehicle control. Densitometry (bar graphs) was performed and relative expression is in reference to the DMSO control at each timepoint (n = 2). X456 cells were assessed for expression of b Sox2, c Nestin, and d GFAP by flow cytometry after 24 h culture with CX-4945 (10 μM) or vehicle control (n = 2). *p < 0.05