TABLE 1.
MICs and MBCs of various antibiotics for B. pseudomallei
Antibiotic | Category | MIC (μg/ml) | MBC (μg/ml) |
---|---|---|---|
Ceftazidime | Cephalosporin | 1 | 2 |
Chloramphenicol | Protein synthesis inhibitor | 8 | >125 |
Doxycycline | Tetracycline | 0.5 | 16 |
Gentamicin | Aminoglycoside | 125 | 250 |
Ofloxacin | Fluoroquinolone | 8 | 32 |
Sulfamethoxazole | Sulfonamide | 250 | >16,000 |
Trimethoprim | Folate synthesis inhibitor | 64 | 500 |
Co-trimoxazole (1:5)a | 64 | 1,000 | |
Co-trimoxazole (2:1)a | 32 | 64 |
Ratio of trimethoprim to sulfamethoxazole (wt/wt).