TABLE 2.
Predominant morphology of B. pseudomallei after 6 h antibiotic exposure
| Antibiotic | Morphology at different MICsa
|
||||||
|---|---|---|---|---|---|---|---|
| 1/16 | 1/8 | 1/4 | 1/2 | 1 | 2 | ≥4 | |
| Ceftazidime | N | N | F | F | F | F | F |
| Chloramphenicol | N | N | N | N | N | N | N |
| Doxycycline | N | N | N | N | N | N | N |
| Gentamicin | N | N | N | N | N | N | N |
| Ofloxacin | N | F | F | F | F | N | N |
| Sulfamethoxazole | N | N | N | N | N | N | N |
| Trimethoprim | F | F | F | F | F | N | N |
| Co-trimoxazole (1:5)b | N | N | N | F | F | F | N |
| Co-trimoxazole (2:1)b | F | F | F | F | N | N | N |
a
The values in the subheads indicate the fractions or multiples of MIC of each antibiotic, with a value of 1 being the MIC of the antibiotic tested. N, nonfilamentous form; F, filamentous form.
b
Ratio of trimethoprim to sulfamethoxazole (wt/wt).