TABLE 3.
MICs of antibiotics for revertants of ceftazidime-induced B. pseudomallei filaments
| Antibiotic | MIC (μg/ml) for revertants previously exposed to the following concn of ceftazidimea:
|
MIC (μg/ml) for untreated control | |
|---|---|---|---|
| 1 μg/ml | 0.5 μg/ml | ||
| Ceftazidime | 4 | 1 | 1 |
| Chloramphenicol | 8 | 8 | 8 |
| Doxycycline | 1 | 1 | 1 |
| Gentamicin | 250 | 125 | 125 |
| Ofloxacin | 16 | 8 | 8 |
| Sulfamethoxazole | 250 | 250 | 250 |
| Trimethoprim | 64 | 64 | 64 |
| Co-trimoxazole (1:5)b | 64 | 64 | 64 |
| Co-trimoxazole (2:1)b | 32 | 32 | 32 |
a
Data in boldface indicate an increase in the MIC of the antibiotic for the revertants compared to that for the untreated, nonfilamentous control bacteria (data are presented in the last column) in the same experiment.
b
Ratio of trimethoprim to sulfamethoxazole (wt/wt).