TABLE 1.

Summary of treatment-emergent adverse events by dose cohort

Event category	No. of adverse events in dose cohort
	2 mg/kg	5 mg/kg	10 mg/kg	20 mg/kg	Total
Possibly related adverse event
Headache	1	1	0	1	3
Neutropenia	0	0	0	1	1
Gastroesophageal reflux disorder	1	0	0	0	1
Erythema	0	1	0	0	1
Severity
Mild	11	9	7	3	30
Moderate	1	0	0	0	1