TABLE 2.
Comparison of MICs of fluoroquinolones between nalidixic acid-resistant and susceptible S. sonnnei isolates
| Phenotype for NA resistance or susceptibility | No. of strains for which fluoroquinolone MIC (μg/ml) is:
|
Breakpoint for reduced susceptibility to fluoroquinolones tested | |||||||
|---|---|---|---|---|---|---|---|---|---|
| 0.008 | 0.016 | 0.032 | 0.064 | 0.125 | 0.25 | 0.5 | 1 | ||
| Ciprofloxacin | |||||||||
| NA-R | 1 | 3 | 5 | 6 | 0.125 | ||||
| NA-S | 37 | 4 | 2 | ||||||
| Norfloxacin | |||||||||
| NA-R | 1 | 1 | 6 | 7 | 0.25 | ||||
| NA-S | 3 | 3 | 35 | 2 | |||||
| Ofloxacin | |||||||||
| NA-R | 1 | 3 | 3 | 8 | 0.25 | ||||
| NA-S | 3 | 37 | 3 | ||||||
| Levofloxacin | |||||||||
| NA-R | 1 | 1 | 3 | 10 | 0.125 | ||||
| NA-S | 12 | 27 | 4 | ||||||
| Sparfloxacin | |||||||||
| NA-R | 1 | 4 | 1 | 9 | 0.064 | ||||
| NA-S | 14 | 24 | 5 | ||||||
a
NA-R; NA-resistant strain, NA-S; NA-susceptible strain.