TABLE 3.
MICs of NA-resistant S. sonnnei strains
| Parameter (no. of strains) | MIC (μg/ml)
|
|||||
|---|---|---|---|---|---|---|
| Nalidixic acid | Ciprofloxacin | Norfloxacin | Ofloxacin | Levofloxacin | Sparfloxacin | |
| gyrA mutation in codon 87 (5) | ||||||
| Range | 64->256 | 0.008-0.125 | 0.032-0.5 | 0.032-0.5 | 0.016-0.125 | 0.008 |
| MIC50 | 64 | 0.004 | 0.25 | 0.25 | 0.125 | 0.064 |
| MIC90 | >256 | 0.125 | 0.5 | 0.5 | 0.125 | 0.064 |
| gyrA mutation in codon 83 (10)a | ||||||
| Range | >256 | 0.125-0.25 | 0.5-1 | 0.5-1 | 0.25 | 0.125-0.25 |
| MIC50 | >256 | 0.25 | 1 | 1 | 0.25 | 0.25 |
| MIC90 | >256 | 0.25 | 1 | 1 | 0.25 | 0.25 |
a
Domestic and imported strains.