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Diagnostic performance of R-HE4 in differentiating OC patient from non-OC objects (HC and CKD). R-HE4 provides a sensitivity of 82.6% and a specificity of 85.4% in OC diagnosis based on a diagnosis interval from 36.85 to 96.15. R-HE4, ratio of urinary-to-serum HE4 level; OC, ovarian cancer; CKD, chronic kidney disease; HC, healthy control. The non-OC objects refer to HC and CKD subjects.
