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Comparison of local recurrence after RFA abutting the sub-diaphragm as determined from the use, or not, of CEUS ultrasonography with Sonazoid™. The rate of local recurrence in contrast ultrasonographic RFA with Sonazoid™ was 0.0, 0.0, and 5.9% at 6, 12, and 24 months, respectively. The rate of contrast ultrasonography without Sonazoid™ was 20.6, 31.0 and 31.0% over 6, 12 and 24 months, respectively (P=0.0052). CEUS, contrast-enhanced ultrasonography.
