Fig. 2.

Experimental challenge of immunized mice (Experiment I). a Mean and standard deviation log₁₀ values of parasitaemia in mice immunized with 30 YU of N-PbCS, PbCS, N, or WT non-adjuvanted yeast lysates, and in non-immunized mice following infection with 8 × 10³ GFP⁺ P. berghei sporozoites at day 0. Asterisks indicate significant median differences (two symbols for p < 0.005, three for p < 0.0005; Mann–Whitney nonparametric test). b Parasitaemia at day 5 post challenge. Bars correspond to medians. Asterisks indicate significant median differences (two symbols for p < 0.005, Mann–Whitney nonparametric test). Decrease in parasitaemia median value in N-PbCS immunized group in comparison with the naive group is indicated in folds