Table V.
Differentially expressed miRNAs in MNA vs. MNnA NB tumours.
| miRNA | log2FC | FDR | Status | Refs. | MYCN-binding motif |
|---|---|---|---|---|---|
| miR-517b-3p | 7.40 | 0.01263 | Upregulated | Novel in NB | 0 |
| miR-183-5p | 4.07 | 0.01311 | Upregulated | (52) | 0 |
| miR-182-5p | 3.93 | 0.01263 | Upregulated | (53) | 0 |
| miR-451a | 3.45 | 0.01851 | Upregulated | (61) | 0 |
| miR-217 | 3.29 | 0.00962 | Upregulated | Novel in NB | 0 |
| miR-18b-5p | 3.18 | 0.01137 | Upregulated | (18) | 2 |
| miR-3182 | 2.85 | 0.02742 | Upregulated | Novel in NB | 0 |
| miR-105-5p | 2.84 | 0.03751 | Upregulated | (62) | 0 |
| miR-20a-5p | 2.80 | 0.01263 | Upregulated | (18,48,62,63,74) | 1 |
| miR-130b-3p | 2.79 | 0.01263 | Upregulated | (61) | 0 |
| miR-935 | 2.69 | 0.02807 | Upregulated | (62) | 0 |
| miR-18a-5p | 2.64 | 0.01263 | Upregulated | (56,62,63,74) | 1 |
| miR-130b-5p | 2.64 | 0.01440 | Upregulated | Novel in NB | 0 |
| miR-17-5p | 2.57 | 0.01851 | Upregulated | (18,48,55,62) | 1 |
| miR-301b-3p | 2.44 | 0.03073 | Upregulated | Novel in NB | 0 |
| miR-16-2-3p | 2.38 | 0.01263 | Upregulated | Novel in NB | 0 |
| miR-92a-3p | 2.12 | 0.04003 | Upregulated | (18,55,62,63,76) | 1 |
| miR-489-3p | −3.25 | 0.01263 | Downregulated | Novel in NB | 2 |
| miR-628-5p | −2.53 | 0.01137 | Downregulated | (62,63) | 0 |
| miR-338-5p | −2.40 | 0.01263 | Downregulated | Novel in NB | 1 |
| miR-491-5p | −2.23 | 0.01263 | Downregulated | (76) | 0 |
| miR-628-3p | −2.16 | 0.01851 | Downregulated | (18,48,62,63) | 1 |
| miR-3065-3p | −2.10 | 0.03073 | Downregulated | Novel in NB | 1 |
FDR, false discovery rate; FC, fold-change; NB, neuroblastoma.