Fig. 6.

Model for DNA binding to the S-subunit of an M. janaschii type I R-M system. The model was obtained by transporting the DNA from the TaqI-MTase DNA complex structure to each TRD of the S-subunit after the DNA binding domain of TaqI-MTase was superposed to TRDs of the S-subunit. TRDs interact with the DNA major groove. When the bound DNA in a colored surface presentation is compared with normal B-DNA in a gray surface presentation, the modeled DNA is kinked and twisted toward one end of the DNA.