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. 2017 Jun 29;15:149. doi: 10.1186/s12967-017-1248-y

Fig. 3.

Fig. 3

Proposed algorithm for discriminating among renal cell tumours in tissue samples. High promoter methylation levels of OXR1 combined with MST1R allowed identification of renal cell tumours (RCT) from normal renal tissue, and of clear cell renal cell carcinoma (ccRCC) from the remaining renal cell tumours (RCT). Then, a high promoter methylation level of HOXA9 allowed the identification of oncocytoma from papillary (pRCC) and chromophobe (chRCC) renal cell carcinoma. SE sensitivity, SP specificity, PPV positive predictive value, NPV negative predictive value, Acc accuracy