Table 1. Increase in anti-HBs antibody titer in 9 of 17 volunteers who ate three doses of HBsAg-transgenic potatoes.
Fold increase
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Volunteer no. | Day 0, mlU/ml | Day 7 | Day 14 | Day 21 | Day 28 | Day 35 | Day 42 | Day 56 | Day 70 |
1 | 17 | 1.2 | 4.1 | 8.2 | 15.8 | 25.2 | 23.6 | 27.2 | 29.2 |
2 | 9 | 1.0 | 5.9 | 8.2 | 8.2 | 9.4 | 7.2 | 6.8 | 6.7 |
3 | 20 | 2.1 | 2.9 | 4.2 | 22.6 | 23.8 | 44.9 | 32.6 | 37.3 |
4 | 85 | 0.9 | 5.8 | 14.3 | 36.0 | 42.0 | 48.9 | 53.3 | 56.3 |
5 | 120 | 1.2 | 2.4 | 3.3 | 5.0 | 5.6 | 13.2 | 14.3 | 14.3 |
6 | 72 | 1.1 | 1.9 | 3.8 | 4.9 | 7.3 | 15.3 | 17.0 | 17.0 |
7 | 85 | 0.9 | 1.0 | 0.9 | 1.3 | 2.5 | 2.1 | 1.9 | 1.3 |
8 | 40 | 0.9 | 1.0 | 1.8 | 3.0 | 3.1 | 8.3 | 10.8 | 8.6 |
9 | 50 | 0.9 | 1.1 | 1.5 | 4.5 | 7.3 | 9.3 | 13.3 | 14.9 |
10 | 115 | 1.9 | 4.4 | 9.2 | 17.1 | 26.7 | 25.8 | 30.0 | 28.4 |
Volunteers 1–5 and 10 had at least a 2-fold increase in their individual antibody titers after one dose of trangenic potato eaten on day 0.