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Macrophages in different regions of the mouse spleen and lymph node perform distinct functions in immunity and haemopoietic cell turnover. Schematic representation of regional differences of splenic macrophages in the red and white pulp, as well as the marginal zone. Marginal zone metallophils line vascular sinuses. Lymph nodes contain an analogous population that lines the subcapsular sinus. See text for further details. From [113], with permission
