Table 3B.

Multivariable logistic regression analysis of in-hospital mortality during hospitalizations where mitochondrial disease was noted, stratified by pediatric versus adult age.

	Pediatric (< 21 years), with Mitochondrial Disease		Adult ( 18 years), with Mitochondrial Disease
Factor	Adjusted OR (95% CI)	p-value	Adjusted OR (95% CI)	p-value
Age (per year increase)	1.00 (0.94,1.08)	0.84	0.96 (0.93, 1.00)	0.05
Non-white population ancestry	0.57 (0.29, 1.13)	0.11	0.58 (0.19, 1.78)	0.34
Number of chronic conditions	1.18 (1.02, 1.36)	0.03	1.33 (0.93, 1.88)	0.12
Median household income for participant zip code	1.41 (1.08, 1.84)	0.01	1.11 (0.64, 2.02)	0.67
Emergency room use	3.09 (1.52, 6.28)	.002	1.46 (0.38, 5.72)	0.58
Number of in-hospital diagnoses	0.82 (0.78, 0.88)	< 0.0001	0.84 (0.72, 0.98)	0.03
Major operating room procedure	1.14 (0.56, 2.32)	.73	1.29 (0.23, 7.35)	0.77
Length of stay (per day increase)	1.00 (0.99, 1.02)	.60	0.98 (0.95, 1.00)	0.10

Factors indicated in bold text demonstrated a statistically significant association with in-hospital mortality during hospitalizations where mitochondrial disease was noted (i.e., OR>1 corresponds to increased risk of in-hospital death, OR<1 corresponds to decreased risk of in-hospital death). OR = odds ratio; CI = confidence interval.