Table 2.
External Beam Radiation therapy Only +/−NADT Distribution of participant responses to EPIC Sexual HRQOL items at baseline, 6, 12, and 24 months.
| NADT | No NADT | P value* | |||||
|---|---|---|---|---|---|---|---|
| How would you rate each of the following during the last 4 weeks? | Very poor to none + Poor | Fair + Good + Very good | n | Very poor to none + Poor | Fair + Good + Very good | n | |
| Your ability to have an erection? | 0.0001 | ||||||
| Baseline: | 40.5% | 59.5% | 84 | 35.9% | 64.1% | 198 | |
| 6 months: | 82.6% | 17.4% | 69 | 45.2% | 54.8% | 177 | |
| 12 months: | 77.8% | 22.2% | 72 | 47.1% | 52.9% | 170 | |
| 24 months: | 76.1% | 23.9% | 67 | 48.4% | 51.6% | 157 | |
| How would you describe the usual QUALITY of your erections during the last 4 weeks? | None at all + Not firm for sexual activity | Firm enough masturbation or foreplay + Firm enough for intercourse | None at all + Not firm for sexual activity | Firm enough masturbation or foreplay + Firm enough for intercourse | <.0001 | ||
| Baseline: | 37.0% | 63.0% | 81 | 27.2% | 72.8% | 191 | |
| 6 months: | 81.4% | 18.6% | 70 | 36.6% | 63.4% | 175 | |
| 12 months: | 69.6% | 30.4% | 69 | 37.2% | 62.8% | 164 | |
| 24 months: | 68.2% | 31.8% | 66 | 34.0% | 66.0% | 159 | |
| How would you describe the FREQUENCY of your erections during the last 4 weeks? | Never + Less than half the time wanted + About half the time wanted | More than half the time wanted + Whenever Wanted | Never + Less than half the time wanted + About half the time wanted | More than half the time wanted + Whenever Wanted | 0.0001 | ||
| Baseline: | 45.7% | 54.3% | 81 | 43.4% | 56.6% | 189 | |
| 6 months: | 87.9% | 12.1% | 66 | 52.1% | 47.9% | 169 | |
| 12 months: | 80.6% | 19.4% | 67 | 57.1% | 42.9% | 163 | |
| 24 months: | 81.5% | 18.5% | 65 | 59.9% | 40.1% | 157 | |
| Your ability to reach orgasm (climax)? | <.0001 | ||||||
| Baseline: | 34.6% | 65.4% | 81 | 30.4% | 69.6% | 194 | |
| 6 months: | 84.1% | 15.9% | 69 | 40.5% | 59.5% | 173 | |
| 12 months: | 69.6% | 30.4% | 69 | 43.4% | 56.6% | 166 | |
| 24 months: | 65.2% | 34.9% | 66 | 39.1% | 60.9% | 156 | |
| Overall, how would you rate your ability to function sexually during the last 4 weeks? | Very poor + Poor | Fair + Good + Very Good | Very poor + Poor | Fair + Good + Very Good | <.0001 | ||
| Baseline: | 32.5% | 67.5% | 83 | 34.0% | 66.0% | 194 | |
| 6 months: | 80.9% | 19.1% | 68 | 43.3% | 56.7% | 171 | |
| 12 months: | 74.6% | 25.4% | 67 | 43.4% | 56.6% | 168 | |
| 24 months: | 75.4% | 24.6% | 65 | 44.0% | 56.0% | 159 | |
| Overall, how big a problem has your sexual function or lack of sexual function been for you during the last 4 weeks? | Moderate problem + Big problem | No Problem + Very small problem + Small problem | Moderate problem + Big problem | No Problem + Very small problem + Small problem | 0. 4622 | ||
| Baseline: | 15.5% | 84.5% | 84 | 20.3% | 79.7% | 197 | |
| 6 months: | 34.7% | 65.3% | 72 | 29.5% | 70.5% | 173 | |
| 12 months: | 25.7% | 74.3% | 70 | 29.0% | 71.0% | 169 | |
| 24 months: | 34.9% | 65.2% | 66 | 32.3% | 67.7% | 161 | |
*
P value reflects a test of the interaction term between group and the time points in linear generalized estimating equations (GEE)