Table 3.
Brachytherapy Distribution only +/−NADT of participant responses to EPIC Sexual HRQOL items at baseline, 6, 12, and 24 months.
| NADT | No NADT | P value* | |||||
|---|---|---|---|---|---|---|---|
| How would you rate each of the following during the last 4 weeks? | Very poor to none + Poor | Fair + Good + Very good | n | Very poor to none + Poor | Fair + Good + Very good | n | |
| Your ability to have an erection? | 0.9501 | ||||||
| Baseline: | 35.7% | 64.3% | 14 | 30.5% | 69.5% | 262 | |
| 6 months: | 61.5% | 38.5% | 13 | 49.0% | 51.0% | 241 | |
| 12 months: | 50.0% | 50.0% | 12 | 46.2% | 53.8% | 238 | |
| 24 months: | 58.3% | 41.7% | 12 | 49.6% | 50.5% | 222 | |
| How would you describe the usual QUALITY of your erections during the last 4 weeks? | None at all + Not firm for sexual Activity | Firm enough masturbation or foreplay + Firm enough for intercourse | None at all + Not firm for sexual Activity | Firm enough masturbation or foreplay + Firm enough for intercourse | 0.5041 | ||
| Baseline: | 21.4% | 78.6% | 14 | 20.5% | 79.5% | 254 | |
| 6 months:: | 53.9% | 46.2% | 13 | 39.4% | 60.6% | 236 | |
| 12 months: | 27.3% | 72.7% | 11 | 31.9% | 68.1% | 229 | |
| 24 months: | 36.4% | 63.6% | 11 | 36.4% | 63.6% | 220 | |
| How would you describe the FREQUENCY of your erections during the last 4 weeks? | Never + Less than half the time wanted + About half the time wanted | More than half the time wanted + Whenever Wanted | Never + Less than half the time wanted + About half the time wanted | More than half the time wanted + Whenever Wanted | 0.3714 | ||
| Baseline: | 35.7% | 64.3% | 14 | 36.4% | 63.6% | 253 | |
| 6 months: | 76.9% | 23.1% | 13 | 56.7% | 43.3% | 231 | |
| 12 months: | 58.3% | 41.7% | 12 | 53.7% | 46.3% | 227 | |
| 24 months: | 66.7% | 33.3% | 12 | 62.0% | 38.0% | 216 | |
| Your ability to reach orgasm (climax)? | 0.6923 | ||||||
| Baseline: | 28.6% | 71.4% | 14 | 23.3% | 76.7% | 253 | |
| 6 months: | 61.5% | 38.5% | 13 | 42.6% | 57.5% | 235 | |
| 12 months: | 36.4% | 63.6% | 11 | 36.1% | 64.0% | 233 | |
| 24 months: | 50.0% | 50.0% | 12 | 43.9% | 56.1% | 221 | |
| Overall, how would you rate your ability to function sexually during the last 4 weeks? | Very poor + Poor | Fair + Good + Very Good | Very poor + Poor | Fair + Good + Very Good | 0.5890 | ||
| Prior to NADT: | 35.7% | 64.3% | 14 | 26.9% | 73.1% | 260 | |
| 6 months: | 61.5% | 38.5% | 13 | 46.9% | 53.1% | 239 | |
| 12 months: | 45.5% | 55.6% | 11 | 42.2% | 57.8% | 237 | |
| 24 months: | 41.7% | 58.3% | 12 | 46.1% | 53.9% | 219 | |
| Overall, how big a problem has your sexual function or lack of sexual function been for you during the last 4 weeks? | Moderate problem + Big problem | No Problem + Very small problem + Small problem | Moderate problem + Big problem | No Problem + Very small problem + Small problem | 0.8713 | ||
| Baseline: | 21.4% | 78.6% | 14 | 17.7% | 82.3% | 260 | |
| 6 months: | 46.2% | 53.9% | 13 | 33.1% | 67.0% | 239 | |
| 12 months: | 45.5% | 54.6% | 11 | 29.0% | 71.0% | 238 | |
| 24 months: | 41.7% | 58.3% | 12 | 28.3% | 71.8% | 223 | |
*
P value reflects a test of the interaction term between group and the time points in linear generalized estimating equations (GEE)