Table 5.

Brachytherapy only +/−NADT distribution of participant responses to EPIC Hormone/Vitality HRQOL items at baseline, 6, 12, and 24 months.

	NADT			No NADT			P value*
How big a problem during the last 4 weeks, if any, has each of the following been for you?	Moderate problem + Big problem	No Problem + Very small problem + Small problem	n	Moderate problem + Big problem	No Problem + Very small problem + Small problem	n
Hot flashes[1]							0.1014
Baseline:	0%	100%	14	0.7%	99.3%	270
6 months:	15.4%	84.6%	13	2.4%	97.6%	253
12 months:	0%	100%	12	0.8%	99.2%	250
24 months:	8.3%	91.7%	12	1.3%	98.7%	233
Breast tenderness/enlargement[1]							0.7551
Baseline:	0%	100%	14	0.7%	99.3%	270
6 months:	7.7%	92.3%	13	1.2%	98.8%	253
12 months:	0%	100%	12	0.8%	99.2%	250
24 months:	0%	100%	12	0.9%	99.1%	233
Feeling depressed[1]							0.9208
Baseline:	0%	100%	14	4.1%	95.9%	271
6 months:	15.4%	84.6%	13	4.3%	95.7%	254
12 months:	16.7%	83.3%	12	3.6%	96.4%	249
24 months:	0%	100%	12	5.2%	94.9%	233
Lack of energy							0.3000
Baseline:	7.1%	92.9%	14	6.7%	93.3%	270
6 months:	30.8%	69.2%	13	15.8%	84.3%	254
12 months:	8.3%	91.7%	12	14.4%	85.6%	250
24 months:	8.3%	91.7%	12	11.6%	88.4%	233
Change in body weight[1]							0.0501
Baseline:	0%	100%	14	3.0%	97.1%	271
6 months:	30.8%	69.2%	13	5.9%	94.1%	254
12 months:	16.7%	83.3%	12	7.6%	92.4%	249
24 months:	8.3%	91.7%	12	6.0%	94.0%	233

P value reflects a test of the interaction term between group and the time points in linear generalized estimating equations (GEE).

^[1]Cochran-Mantel-Haenszel test