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. Author manuscript; available in PMC: 2018 Mar 1.

Published in final edited form as: Bull Math Biol. 2017 Jan 18;79(3):448–497. doi: 10.1007/s11538-016-0241-6

Table 5.

The estimates are improved by reducing the size of the bleaching region so as to change the time scale of diffusion relative to that of binding.

True values of parameters			Bleaching region	Observation T	Estimates of parameters

D	k⁺	k⁻	BR	T (sec)	D	k⁺	k⁻

2.5e-4	1	0.1	Default	100	1.9132e-4	0.7542	0.1013
				10	2.5689e-4	0.9684	0.09649

			Reduced size	100	2.4228e-4	0.9666	0.09999
				10	2.4364e-4	0.9666	0.09990

2.5e-4	1	1	Default	100	2.0315e-4	0.5236	0.8367
				10	2.1076e-4	0.5543	0.8183

			Reduced size	100	2.4891e-4	0.9912	0.9997
				10	2.4888e-4	0.9916	0.9999

2.5e-4	0.1	1	Default	100	2.3841e-4	0.02947	0.6054
				10	2.4728e-4	0.04320	0.5689

			Reduced size	100	2.4987e-4	0.09936	0.9995
				10	2.4988e-4	0.09935	0.9994