Table 1.
Results from conditional logistic regression analyses of pre-symptomatic individuals compared with controls presented for all individuals and stratified for women and men, respectively
| Pre-symptomatic individuals (n = 547) | Controls (n = 1641) | OR (95% CI) | Pre-symptomatic women (n = 372) | Control women (n = 1116) | OR (95% CI) | Pre-symptomatic men (n = 175) | Control men (n = 525) | OR (95% CI) | |
|---|---|---|---|---|---|---|---|---|---|
| Smoking evera | 366/540 (67.8) | 823/1609 (51.1) | 2.01 (1.64–2.47) | 241/366 (65.8) | 548/1096 (50.0) | 1.92 (1.50–2.47) | 125/174 (71.8) | 275/513 (53.6) | 2.23 (1.53–3.27) |
| Current smokera | 197/538 (36.6) | 326/1603 (20.3) | 2.74 (2.15–3.51) | 133/365 (36.4) | 245/1094 (22.4) | 2.01 (1.54–2.61) | 64/173 (37.0) | 81/509 (15.9) | 3.11 (2.09–4.64) |
| Ex smokera | 167/538 (31.0) | 491/1603 (30.6) | 1.52 (1.19–1.95) | 107/365 (29.3) | 301/1094 (27.5) | 1.56 (1.16–2.10) | 60/173 (34.7) | 190/509 (37.3) | 1.49 (0.97–2.30) |
| Oral tobacco (snuff) | 102/494 (20.6) | 278/1491 (18.6) | 1.22 (0.91–1.63) | 22/329 (6.7) | 77/998 (7.7) | 0.93 (0.56–1.55) | 80/165 (48.5) | 201/493 (40.8) | 1.40 (0.97–2.00) |
| BMI (kg/m2)b | 25.7 (23.1–28.6) (n = 544) | 25.3 (23.1–28.1) (n = 1634) | 1.03 (1.00–1.05) | 25.5 (22.8–28.6) (n = 369) | 25.5 (22.8–28.6) (n = 1111) | 1.03 (1.00–1.06) | 26.0 (24.0–28.4) (n = 175) | 26.0 (24.0–28.4) (n = 523) | 1.02 (0.98–1.07) |
| Waistc (cm) | 93.0 (82.0–102.0) (n = 103) | 89.0 (81.0–97.0) (n = 307) | 1.02 (1.00–1.04) | 85.5 (78.8–100.0) (n = 70) | 85.0 (78.0–93.0) (n = 204) | 1.02 (1.00–1.04) | 98.0 (93.5–107.0) (n = 33) | 96.0 (90.0–102.0) (n = 103) | 1.03 (0.99–1.07) |
| Low education levelb,d | 452/540 (83.7) | 1273/1613 (78.9) | 1.41 (1.07–1.84) | 294/366 (80.3) | 854/1101 (77.6) | 1.21 (0.88–1.65) | 158/174 (90.8) | 419/512 (81.8) | 2.15 (1.23–3.78) |
| Hypertensive treatment | 76/451 (16.9) | 242/1333 (18.2) | 0.84 (0.61–1.15) | 47/306 (15.4) | 168/899 (18.7) | 0.70 (0.47–1.04) | 29/145 (20.0) | 74/434 (17.1) | 1.20 (0.70–2.07) |
| Lipid lowering treatment | 14/390 (3.6) | 47/1164 (4.0) | 0.73 (0.36–1.47) | 6/266 (2.3) | 24/773 (3.1) | 0.46 (0.15–1.42) | 8/124 (6.5) | 23/391 (5.9) | 1.06 (0.42–2.68) |
Data presented as n (%) or median (Q1–Q3)
Odds ratio (OR) with 95% confidence interval (CI) in conditional logistic regression
BMI body mass index
aReference group being never smoker
bOR per unit of increase
cWaist as continuous variable
dLow education level = no academic education/university