TABLE 1.
Epidemiological and clinical characteristics
| Patient characteristica | Value for all groups (n = 48) | Value for patients in indicated postoperative alteration pattern groupb
|
P | ||
|---|---|---|---|---|---|
| Overall enhanced (n = 10) | Mixed (n = 20) | Overall attenuated (n = 18) | |||
| Agee (yr) | 66 ± 1.3 | 68 ± 3.5 | 64 ± 2.4 | 68 ± 1.5 | 0.509c |
| No. of patients | |||||
| Female/male | 12/36 | 2/8 | 6/14 | 4/14 | 0.789d |
| Receiving anesthesia | |||||
| General | 14 | 4 | 5 | 5 | |
| Locoregional | 34 | 6 | 15 | 13 | 0.686d |
| Duration of surgerye (min) | 97 ± 5 | 102 ± 10 | 100 ± 9 | 90 ± 9 | 0.399c |
| Infusion during surgerye (liters) | |||||
| Crystalloids | 1.7 ± 0.1 | 1.8 ± 0.4 | 1.8 ± 0.2 | 1.4 ± 0.4 | 0.139c |
| Colloids | 0.8 ± 0.06 | 0.9 ± 0.2 | 0.9 ± 0.1 | 0.8 ± 0.1 | 0.669c |
| Hemoglobin levele (mg/dl) | |||||
| Pre | 12.7 ± 0.3 | 12.3 ± 0.5 | 13.3 ± 0.5 | 12.3 ± 0.5 | 0.295c |
| Post | 10.6 ± 0.2 | 11.1 ± 0.5 | 10.5 ± 0.4 | 10.4 ± 0.3 | 0.247c |
| No. of patients receiving autologous blood transfusion/no. receiving heterologous transfusion | |||||
| 0 U | 25/41 | 4/6 | 13/18 | 8/17 | |
| 1 U | 10/1 | 2/1 | 3/0 | 5/0 | |
| 2 U | 10/1 | 2/1 | 4/0 | 4/0 | 0.403d,f |
| 3 U | 3/5 | 2/2 | 0/2 | 1/1 | 0.130d,g |
| No. of WBC/nle | |||||
| Pre | 6.5 ± 0.4 | 7.0 ± 1.3 | 6.9 ± 0.4 | 5.7 ± 0.4 | 0.237c |
| Post | 7.5 ± 0.4 | 6.6 ± 0.6 | 7.7 ± 0.7 | 7.8 ± 0.5 | 0.369c |
| Tempe (°C) | |||||
| Pre | 36.8 ± 0.1 | 36.8 ± 0.1 | 36.8 ± 0.1 | 36.9 ± 0.1 | 0.669c |
| Post | 37.5 ± 0.1 | 37.4 ± 0.1 | 37.6 ± 0.1 | 37.5 ± 0.1 | 0.610c |
a
Pre, preoperative; Post, postoperative; Temp, rectal body temperature.
b
Data are for patients with different alteration patterns of cytokine (TNF-α, IL-6, and IL-8) production.
c
Values determined by MWU.
d
Values determined by χ2.
e
Data in each row are given as means ± standard deviations except where otherwise indicated.
f
P values represent the levels of statistical significance for differences in autologous blood transfusion between patients with different alteration patterns.
g
P values represent the levels of statistical significance for differences in heterologous blood transfusion between patients with different alteration patterns.