Table 3.
Proteins that are differentially expressed with a ≥2.0-fold-change in the synovial fluid collected at Stage I compared to Stage II of the ACI procedure in clinical responders
| Protein | Fold change | |
|---|---|---|
| Description | Accession | |
| Heat shock protein 75 kDa, mitochondrial | Q12931 | –470.0 |
| Microtubule-associated protein 1B | P46821 | –17.2 |
| Adenosylhomocysteinase | P23526 | –3.7 |
| Complement factor H-related protein 3 | Q02985 | –2.8 |
| Mannose-1-phosphate guanyltransferase beta | Q9Y5P6 | –2.7 |
| Peroxiredoxin-4 | Q13162 | –2.5 |
| Oxysterol-binding protein 1 | P22059 | –2.4 |
| Protein canopy homolog 3 | Q9BT09 | –2.1 |
| Spermatid perinuclear RNA-binding protein | Q96SI9 | –2.0 |
| Ferritin light chain | P02792 | 2.2 |
| Secreted phosphoprotein 24 | Q13103 | 2.2 |
| Chondroitin sulfate proteoglycan 4 | Q6UVK1 | 2.3 |
| Collagen alpha-2(I) chain | P08123 | 2.3 |
| Collagen alpha-1(V) chain | P20908 | 2.5 |
| 26S protease regulatory subunit 6A | P17980 | 2.7 |
| Collagen alpha-2(V) chain | P05997 | 2.9 |
| Collagen alpha-1(I) chain | P02452 | 3.3 |
| Spectrin alpha chain, erythrocytic 1 | P02549 | 4.1 |
| Histidine triad nucleotide-binding protein 1 | P49773 | 4.2 |
| Platelet factor 4 | P02776 | 4.2 |
| Alpha-1-acid glycoprotein 2 | P19652 | 4.3 |
| Protein 4.1 | P11171 | 4.3 |
| Periostin | Q15063 | 4.5 |
| 26S proteasome non-ATPase regulatory subunit 13 | Q9UNM6 | 4.6 |
Positive numbers denote an increase in the protein at Stage II, negative numbers denote a decrease in the protein at Stage II