TABLE 5.
Effect of polymyxin B on cytokine profiles of T-cell lines
| T-cell line | % Positivea for:
|
|||||
|---|---|---|---|---|---|---|
| CD4 cells
|
CD8 cells
|
|||||
| IL-4 | IFN-γ | IL-10 | IL-4 | IFN-γ | IL-10 | |
| 16/PgOM+ | 84.79 | 74.68 | 3.82 | 89.36 | 86.46 | 62.14 |
| 16/PgOM+ (poly- myxin B added) | 91.21 | 66.57 | 9.92 | 95.48 | 83.63 | 50.53 |
| 16/hHSP60+ | 100.00 | 79.13 | 10.40 | 98.24 | 90.55 | 84.67 |
| 16/hHSP60+ (poly- myxin B added) | 98.25 | 60.22 | 4.43 | 98.20 | 95.18 | 79.26 |
| 16/GroEL+ | 68.27 | 11.07 | 4.67 | 81.58 | 78.52 | 80.01 |
| 16/GroEL+ (poly- myxin B added) | 68.46 | 9.88 | 8.28 | 93.38 | 72.05 | 82.92 |
a
Values are percent positive values for each cytokine (one sample per group) of T cells treated with or without polymyxin B (10 μg/ml).