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. Author manuscript; available in PMC: 2017 Jun 30.
Published in final edited form as: Bioconjug Chem. 2016 Oct 14;28(1):203–211. doi: 10.1021/acs.bioconjchem.6b00529

Figure 5.

Figure 5

Simultaneous detection of nucleic acid and protein targets using biotin—PEG—AuNP probes. (a) Detection of positive control molecules (PEG—biotin and biotinylated BSA); 3σ threshold = 315 au. (b) Detection of miRNA and positive control molecules (PEG—biotin and biotinylated BSA);, 3σ threshold = 216 au. (c) Detection of PSA protein and positive control molecules (PEG—biotin and biotinylated BSA); 3σ threshold = 105 au. (d) Simultaneous detection of miRNA, PSA, and positive control molecules (PEG—biotin and biotinylated BSA); 3σ threshold = 339 au.