Table 2. MiRNA concentrations in urine of RCC patients and healthy controls.
miRNA | RCC patients | Healthy controls | P-value | AUC | Sens. (%) | Spec. (%) |
---|---|---|---|---|---|---|
let-7a, fmol/L | 7.510 (2.668–14.250) | 1.525 (0.673–3.368) | < 0.001 | 0.83 | 71 | 81 |
let-7b, fmol/L | 3.500 (1.835–6.160) | 1.350 (0.1400–2.880) | < 0.001 | 0.75 | 73 | 67 |
let-7c, fmol/L | 9.390 (4.090–18.82) | 5.115 (2.180–9.253) | 0.005 | 0.67 | 65 | 62 |
let-7d, fmol/L | 5.540 (2.450–11.88) | 3.505 (1.705–5.145) | 0.006 | 0.66 | 66 | 61 |
let-7e, fmol/L | 58.9 (25.03–106.6) | 32.35 (15.33–63.60) | 0.015 | 0.65 | 62 | 61 |
let-7g, fmol/L | 22.48 (11.46–35.19) | 12.89 (5.72–19.64) | 0.002 | 0.69 | 70 | 60 |
Values of MiRNA concentrations are presented as median (interquartile range). AUC - Area under curve; Sens. – Sensitivity; Spec. – Specificity. |