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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Free Radic Biol Med. 2017 Apr 7;108:362–373. doi: 10.1016/j.freeradbiomed.2017.04.004

Fig 5. Deletion of inducible superoxide dismutase genes reduces lifespan and exacerbates abnormal physiological rates in isp-1 worms.

Fig 5

A. isp-1 worms have increased lifespan compared to wild-type worms. Deletion of either sod-3 or sod-5 significantly decreases the lifespan of isp-1 worms. (B) isp-1 worms develop slower than wild-type worms. The post-embryonic development time of isp-1 worms was further slowed by deletion of sod-3 or sod-5. (C) isp-1 worms have decreased brood size compared to wild-type worms. isp-1 brood size is further decreased by deletion of sod-3 or sod-5. (D) The defecation cycle length of isp-1 worms is slower than wild-type worms. This phenotype is exacerbated by deletion of sod-3 or sod-5. (E) The thrashing rate of isp-1 worms is slower than wild-type worms and is further decreased by deletion of sod-3 or sod-5. Note that the deletion of sod-3 or sod-5 has no effect on any of these phenotypes in wild-type worms. Error bars indicate SEM. *p<0.05, **p<0.01, ***p<0.001.