Figure 4.

Functional Analysis of the HeLa Proteome

(A) Comparison of protein-coding gene abundances in HeLa identified in this dataset with the largest existing HeLa proteome published so far.

(B) Comparison of protein-coding genes identified in HeLa in this dataset with previously published proteome and next-generation RNA-seq data of HeLa cells.

(C) CORUM protein complex coverage of the identified proteins in this dataset.

(D) Abundance of BRCA1/RNA polymerase II complex members in HeLa cells visualized according to their individual protein intensities.

(E) Abundance of proteasomal proteins in HeLa visualized according to their individual protein intensities.

(F) Scatterplot of HeLa protein copy-number estimation from this dataset with previously published copy numbers.