Table 1. Baseline Characteristics of Patients by Repeated Culture Results.
Baseline characteristic data for 299 patients with a repeated fungal culture performed 6 days after enrollment in the Mycotic Ulcer Treatment Trial-I. Patient characteristics are stratified by their day-6 culture results.
| Baseline Characteristic | Fungal Culture Positive on Day 6 (N=92) | Fungal Culture Negative on Day 6 (N=207) |
|---|---|---|
| Gender, N | ||
| Male | 43 (14%) | 87 (29%) |
| Female | 49 (16%) | 120 (40%) |
| Age (years), median (25th, 75th Percentile) | 45 (38, 55) | 48 (38,58) |
| Occupation, N | ||
| Agriculture | 34 (28%) | 100 (33%) |
| Non-Agriculturea | 58 (19%) | 107 (36%) |
| Medication use at enrollmentb, N | ||
| Topical ocular antifungals | 37 (12%) | 101 (34%) |
| Other topical ocular dropsc | 50 (17%) | 128 (43%) |
| Systemic antifungals | 1 (1%) | 10 (3%) |
| Other systemic | 26 (9%) | 54 (18%) |
| Trauma/Injury, N | ||
| Vegetative Matter/Wood | 25 (8%) | 47 (16% ) |
| Metal/Otherd | 33 (11%) | 74 (25%) |
| Unknown Object | 3 (1%) | 11 (4%) |
| Contact Lens | 0 (0%) | 0 (0%) |
| Affected Eye, N | ||
| Right | 115 (38%) | 40 (13%) |
| Left | 92 (31%) | 52 (17%) |
| Visual Acuity (logMAR), median (25th, 75th percentiles) | 0.72 (0.46, 1.02) | 0.64 (0.38, 0.88) |
| Infiltrate/Scar Size (mm1), median (25th, 75th percentiles) | 3.39(2.95, 4.08) | 3.14(2.40, 3.99) |
| Hypopyon | ||
| no | 50 (17%) | 147 (49%) |
| <0.5mm | 20 (7%) | 32 (11%) |
| >0.5mm | 22 (7%) | 28 (9%) |
| Depth | ||
| >0–33% | 47 (16%) | 111 (37%) |
| >33–67% | 36 (12%) | 76 (25%) |
| >67–100% | 9 (3%) | 19 (6%) |
| Epithelial Defect (mm1), median (25th, 75th percentiles) | 2.97 (2.00,3.66) | 2.30 (1.41,3.39) |
| Duration of Symptoms, days, median (25th, 75th percentiles) | 5 (4,10) | 6 (3,10) |
| Systemic disease, N | 9 (3%) | 31 (10.4%) |
a
Includes unemployed, retired, etc.
b
Some patients were on more than one medication at enrollment
c
Includes topical antibiotics, dilating drops, glaucoma medication, lubricating drops
d
Includes dust, finger, kerosene, cement, fingernail, chili powder, sand, cow’s tail, insect