Table 2. Logistic analysis to identify the factors associated with late initiation of combination antiretroviral therapy.

Variables	Univariate analysis		Multivariable analysis*
	OR (95% CI)	P	AOR (95% CI)	P
Age, per 1-year increase	1.04 (1.03–1.04)	<0.001	1.05 (1.04–1.06)	<0.001
Male sex	0.99 (0.72–1.37)	0.966	0.95 (0.64–1.40)	0.784
Mode of HIV exposure
Homosexual sex	1.00 (reference)		1.00 (reference)
Heterosexual sex	1.81 (1.38–2.39)	<0.001	0.99 (0.71–1.39)	0.970
Intravenous drug use	0.70 (0.57–0.85)	<0.001	0.51 (0.35–0.75)	0.001
Region of HIV care
Northern Taiwan	1.00 (reference)		1.00 (reference)
Central Taiwan	1.68 (1.38–2.03)	<0.001	1.78 (1.45–2.19)	<0.001
Southern Taiwan	1.62 (1.35–1.96)	<0.001	1.65 (1.35–2.00)	<0.001
HBsAg seropositivity	1.54 (1.25–1.91)	<0.001	1.31 (1.04–1.64)	0.020
HCV seropositivity	0.67 (0.56–0.81)	<0.001	0.68 (0.48–0.96)	0.030
Year of cART initiation
June 2012—May 2013	1.00 (reference)		1.00 (reference)
June 2013—May 2014	0.74 (0.61–0.89)	0.002	0.77 (0.63–0.93)	0.008
June 2014—May 2015	0.71 (0.59–0.86)	<0.001	0.72 (0.59–0.88)	0.001
June 2015—May 2016	0.60 (0.49–0.74)	<0.001	0.65 (0.52–0.81)	<0.001

Abbreviations: AOR, adjusted odds ratio; CI, confidence interval; HBsAg, hepatitis B surface antigen; HCV, hepatitis C virus; OR, odds ratio.

*All variables in univariate analyses were selected for subsequent multivariable analyses.