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(A) Serum level of total cholesterol (TC). (B) Serum level of triglycerides. Data are expressed as the mean ± SEM (n = 8). ** P <0.01 vs. control group. # P <0.05, ## P <0.01 vs. model group. && P <0.01 vs. orlistat group. NS: no statistical significance. Model: diet-induced obesity (DIO); Orlistat: orlistat (10 mg/kg/d); Canagliflozin (L): canagliflozin (15 mg/kg/d); Canagliflozin (H): canagliflozin (60 mg/kg/d).
