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(A) DGAT2 mRNA. (B) PPARα mRNA. (C) PPARγ1 mRNA. (D) PPARγ2 mRNA. Data are expressed as the mean ± SEM (n = 3). * P <0.05, ** P <0.01 vs. control group. # P <0.05, ## P <0.01 vs. model group. & P <0.05, && P <0.01 vs. orlistat group. NS: no statistical significance. Model: diet-induced obesity (DIO); Orlistat: orlistat (10 mg/kg/d); Canagliflozin (L): canagliflozin (15 mg/kg/d); Canagliflozin (H): canagliflozin (60 mg/kg/d).
