Table 2. Univariate associations of CK with baseline characters and adiposity measures.
Predictors | Coef. | 95% CI | P value |
---|---|---|---|
Age (per 10 years +) | 2.68 | 0.77 to 4.59 | 0.006 |
Gender, Male | 41.77 | 37.55 to 45.98 | <0.001 |
BMI (per unit kg/m2+) | 4.22 | 3.60 to 4.84 | <0.001 |
SBP (per 10 mmHg +) | 6.47 | 5.21 to 7.72 | <0.001 |
DBP (per 10 mmHg +) | 10.07 | 7.98 to 12.16 | <0.001 |
PP (per 10 mmHg +) | 6.22 | 4.35 to 8.09 | <0.001 |
Heart rate (per beat/minutes +) | 0.06 | -0.17 to 0.28 | 0.625 |
Waist Circumference (per unit cm +) | 1.70 | 1.49 to 1.90 | <0.001 |
Fat Mass (per unit kg +) | 0.74 | 0.28 to 1.27 | 0.008 |
Fasting Sugar (per unit mg/dL +) | 0.01 | -0.07 to 0.09 | 0.758 |
HbA1c (per unit %+) | 1.39 | -1.05 to 3.83 | 0.264 |
Uric acids (per unit mg/dL+) | 9.43 | 8.09 to 10.77 | <0.001 |
Triglyceride (per unit mg/dL+) | 0.04 | 0.02 to 0.06 | <0.001 |
Cholesterol (per unit mg/dL+) | 0.07 | 0.01 to 0.13 | 0.017 |
HDL-C (per unit mg/dL+) | -0.48 | -0.63 to -0.33 | <0.001 |
LDL-C (per unit mg/dL+) | 0.12 | 0.05 to 0.19 | 0.001 |
eGFR (per unit mL/min/1.73 m2 +) | -0.72 | -0.84 to -0.60 | <0.001 |
NAFLD | 14.87 | 11.48 to 18.25 | <0.001 |
Hypertension | 20.69 | 15.77 to 25.61 | <0.001 |
Smoking | 9.25 | 3.31 to 15.19 | 0.002 |
Diabetes Mellitus | 0.1 | -0.07 to 0.17 | 0.424 |
Hyperlipidemia treatment | 19.12 | 5.34 to 32.91 | 0.007 |
Abbreviations: BMI = body mass index; BP = blood pressure; FM = fat mass; eGFR = estimated glomerular filtration rate; CK = creatine kinase; SBP = systolic blood pressure; Coef = coefficient; CI = confidence interval. Note: Regression coefficients (β) represent the change in mean difference in CK (in IU/L) per 1-SD difference in each continuous predictor variable. Other abbreviations as Table 1.