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. 2017 Jun 30;12(6):e0179898. doi: 10.1371/journal.pone.0179898

Table 2. Univariate associations of CK with baseline characters and adiposity measures.

Predictors Coef. 95% CI P value
Age (per 10 years +) 2.68 0.77 to 4.59 0.006
Gender, Male 41.77 37.55 to 45.98 <0.001
BMI (per unit kg/m2+) 4.22 3.60 to 4.84 <0.001
SBP (per 10 mmHg +) 6.47 5.21 to 7.72 <0.001
DBP (per 10 mmHg +) 10.07 7.98 to 12.16 <0.001
PP (per 10 mmHg +) 6.22 4.35 to 8.09 <0.001
Heart rate (per beat/minutes +) 0.06 -0.17 to 0.28 0.625
Waist Circumference (per unit cm +) 1.70 1.49 to 1.90 <0.001
Fat Mass (per unit kg +) 0.74 0.28 to 1.27 0.008
Fasting Sugar (per unit mg/dL +) 0.01 -0.07 to 0.09 0.758
HbA1c (per unit %+) 1.39 -1.05 to 3.83 0.264
Uric acids (per unit mg/dL+) 9.43 8.09 to 10.77 <0.001
Triglyceride (per unit mg/dL+) 0.04 0.02 to 0.06 <0.001
Cholesterol (per unit mg/dL+) 0.07 0.01 to 0.13 0.017
HDL-C (per unit mg/dL+) -0.48 -0.63 to -0.33 <0.001
LDL-C (per unit mg/dL+) 0.12 0.05 to 0.19 0.001
eGFR (per unit mL/min/1.73 m2 +) -0.72 -0.84 to -0.60 <0.001
NAFLD 14.87 11.48 to 18.25 <0.001
Hypertension 20.69 15.77 to 25.61 <0.001
Smoking 9.25 3.31 to 15.19 0.002
Diabetes Mellitus 0.1 -0.07 to 0.17 0.424
Hyperlipidemia treatment 19.12 5.34 to 32.91 0.007

Abbreviations: BMI = body mass index; BP = blood pressure; FM = fat mass; eGFR = estimated glomerular filtration rate; CK = creatine kinase; SBP = systolic blood pressure; Coef = coefficient; CI = confidence interval. Note: Regression coefficients (β) represent the change in mean difference in CK (in IU/L) per 1-SD difference in each continuous predictor variable. Other abbreviations as Table 1.