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. 2017 Jun 30;12(6):e0180217. doi: 10.1371/journal.pone.0180217

Fig 10. Expression of Igfn1 exon 13 CRISPR/Cas9 in vivo does not cause significant fibre size change.

Fig 10

A) Fluorescence images of cross sections from whole EDL/TA muscles electroporated with Igfn1 exon 13 CRISPR/Cas9 +tdTomato or tdTomato alone, as indicated. B) Box and whisker plots showing the upper and lower quartiles of cross sectional area measurements for Igfn1 exon 13 CRISPR/Cas9+tdTomato transfected (IGFN1 CRISPR/td) and non-transfected fibres and for tdTomato (td) transfected and non-transfected fibres. Quantifications were carried out for three mice independently, as indicated. Horizontal and vertical bars represent the median and range of values, respectively. Mann-Whitney U test showed no significant difference between transfected and non-transfected fibres.