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Southern blot autoradiogram of HindIII digests of lymphoblastoid DNA from the mother, father, and proposita with the 15q26.1→qter deletion detected by two probes [IGF1R and SGNE-1(7B2)], both localized to different regions of chromosome 15. The intensity of the IGF1R band is approximately one-half that of the SGNE-1 (7B2) band in the proposita, which indicates that an IGF1R gene copy is missing.
