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. Author manuscript; available in PMC: 2017 Jun 30.
Published in final edited form as: J Med Chem. 2017 Apr 3;60(7):3070–3081. doi: 10.1021/acs.jmedchem.7b00109

Figure 4. Radioligand 6H-U69593 competition binding assays for the best hit analogs.

Figure 4

Binding curves shown for the best sub-micromolar compounds resulted from initial scaffold optimization (see also Table 2 and Chart 3). Normalized results (mean ± SEM) from three independent assays (each in triplicate) were pooled and analyzed in GraphPad Prism.