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. 2017 Jun 30;12(6):e0180455. doi: 10.1371/journal.pone.0180455

Fig 1. TEMPOL does not effect water consumption or body mass.

Fig 1

At the onset of hypoxic exposure, (A) water consumption (ml/day), (B) body mass (g), and (C) concentration of TEMPOL (mg/kg/day) dropped significantly. Water consumption and TEMPOL concentration was largely restored after 1 wk hypoxia. Body mass also increased following 1 wk chronic hypoxia in a parallel fashion to normoxic rats but remained lower due to the initial weight loss. There were no differences between SU5416- and vehicle-treated animals; therefore, data were grouped together for this analysis. Values are means ± SE; n = 10 animals/group. *P < 0.05 hypoxia vs. normoxia; there was no difference between vehicle and TEMPOL treated. Data analyzed with two-way ANOVA and individual groups compared with the Student-Newman-Keuls test.