Table 1.
Baseline participant characteristics by sex and incident Alzheimer's disease (AD)
| Men | Women | |||||
|---|---|---|---|---|---|---|
| Variable | Developed AD (N=119) N(%)/mean (SD) | No AD (N=507) N(%)/mean (SD) | p-value | Developed AD (N=73) N(%)/mean (SD) | No AD (N=293) N(%)/mean (SD) | p-value |
| Age | 64.6 (8.8) | 62.2 (7.7) | 0.003 | 68.8 (8.9) | 63.6 (8.0) | <0.001 |
| African American | 8 (6.7%) | 50 (9.9%) | 0.379 | 4 (5.5%) | 63 (21.5%) | 0.001 |
| Education | 17.0 (2.9) | 16.7 (2.7) | 0.334 | 15.8 (2.3) | 15.7 (2.6) | 0.697 |
| Ever Smoking | 89 (74.8%) | 363 (71.6%) | 0.570 | 37 (50.7%) | 135 (46.1%) | 0.514 |
| Body Mass Index | 25.4 (2.4) | 26.4 (3.7) | 0.004 | 25.0 (4.6) | 25.9 (4.6) | 0.163 |
| Diagnosis of Hypertension | 28 (23.5%) | 150 (30.0%) | 0.213 | 16 (21.9%) | 69 (23.6%) | 0.451 |
| Myocardial Infarction | 22 (4.3%) | 2 (1.7%) | 0.285 | 0 | 1 (0.34%) | 1.000 |
| Diabetes | 0.934 | 0.464 | ||||
| None | 59 (49.6%) | 250 (49.3%) | 57 (78.1%) | 232 (79.2%) | ||
| Pre-diabetes | 49 (41.2%) | 203 (40.0%) | 15 (20.6%) | 49 (16.7%) | ||
| Diabetes | 11 (9.2%) | 54 (10.7%) | 1 (1.4%) | 12 (4.1%) | ||
| Apoe E4 allele | 35 (29.4%) | 119 (23.5%) | 0.193 | 30 (41.1%) | 80 (27.3%) | 0.032 |
| Total cholesterol | 230.5 (44.9) | 219.5 (39.3) | 0.008 | 237.7 (34.9) | 227.0 (42.0) | 0.046 |
| Triglycerides | 101.8 (45.8) | 121.0 (83.7) | 0.016 | 96.5 (42.9) | 111.8 (85.9) | 0.141 |
| Statin Use | 3 (2.5%) | 34 (6.7%) | 0.087 | 4 (5.5%) | 24 (8.2%) | 0.623 |