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. 2017 May 26;6(5):e143. doi: 10.1038/cti.2017.18

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Copyright © 2017 The Author(s)

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Helios expression in Treg fractions is associated with a greater percentage of CD4⁺ T cells expressing the regulatory cytokine, IL-10. The percentage of IL-10⁺ CD4⁺ T cells positively correlated with Helios MFI in FrI Treg (rho=0.602, P=0.002) (a), FrII Treg (rho=0.636, P=0.001) (b) and FrIII non-Treg (rho=0.637, P=0.001) (c). Data are for n=23 individuals (n=11 CIS and n=12 HC).