Table 2. Case histology chronology.
| Age | Complication | Hb (g l−1) | N (× 109 l−1) | Plt (x109 l−1) | IgG (g l−1) | IgA (g l−1) | IgM (g l−1) | CD19 (× 109 l−1) | Treatment |
|---|---|---|---|---|---|---|---|---|---|
| 0.9 | T1D | 13.3 | 1.8 | 250 | Insulin | ||||
| 2.3 | ITP | 12.9 | 2.1 | 13 | >30 | 1.7 | 0.7 | IVIg | |
| 2.8 | AIHA, ITP | 7.0 | 1.6 | 1 | IVIg, prednisolone | ||||
| 3.0 | ITP | 12.5 | 5.5 | 3 | IVIg, prednisolone | ||||
| 3.2 | ITP | 13.6 | 3.9 | 21 | RTX | ||||
| 4.2 | Pneumonia, OM, gastroenteritis | 12.9 | 3.2 | 255 | <1 | 0.05 | 0.05 | 0 | Antibiotics |
| 5.2 | Pneumonia (CMV), LIP, HS | 11.1 | 2.1 | 148 | 4.5 | 0.05 | 1.65 | 0.3 | GCV, VCZ, IVIg, MP |
| 6.5 | Pneumonia (Haemophilus influenzae), LIP, HS | 11.8 | 2.4 | 171 | 6.9 | 0.05 | 4.99 | 3.6 | IVIg, MP, MMF |
| 7.9 | LIP, HS | 12.3 | 1.7 | 268 | ABCT, IVIg |
Abbreviations: ABCT, abatacept; AIHA, autoimmune haemolytic anaemia; CMV, cytomegalovirus; GCV, ganciclovir; HS, hepatosplenomegaly; ITP, immune-mediated thrombocytopenia; IvIg, intravenous immunoglobulin; LIP, lymphocytic interstitial pneumonitis; MMF, mycophenolate mofetil; MP, methylprednisolone; OM, otitis media; RTX, rituximab; T1D, type 1 diabetes; VCZ, voriconazole.