Figure 5. TWEAK synergizes with IL-13 and IL-17A to induce chemokines in human keratinocytes.

(a) Basal surface expression of Fn14 (line) on NHEK cells relative to Isotype staining (grey). (b,c) NHEK cells were stimulated for 48 h with rTWEAK, rIL-13, rIL-17 or their combination. mRNA expression of indicated chemokines was assessed relative to GAPDH. Means of triplicate cultures with standard deviations. Values were compared using Student's t-test. One out of three independent experiments.