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. 2017 Jun 30;7:4456. doi: 10.1038/s41598-017-04780-9

Table 2.

Selected characteristics of controls according to C-reactive protein level.

Quartile of C-reactive protein (mg/L) P trend
Lowest Second Third Highest
Men, n (%) 87 (20.5) 108 (25.4) 118 (27.8) 112 (26.4)
Women, n (%) 77 (33.2) 50 (21.5) 51 (22.0) 54 (23.3)
Continuous variables
  Age (years), median (IQR) 58 (54.5–62.5) 60 (56.0–65.0) 60 (56.0–64.0) 61 (56.0–64.0) 0.081
  BMI (kg/m2), median (IQR) 21.6 (20.1–23.4) 22.9 (20.9–24.2) 23.3 (21.3–25.0) 23.9 (22.2–25.9) <0.0001
  Physical activity (METs-hour/day), median (IQR) 35.5 (31.5–39.7) 34.3 (31.4–38.8) 33.9 (30.8–38.1) 34.1 (31.9–38.3) 0.40
  Total energy (kcal/day), median (IQR) 1870 (1664–2240) 1834 (1553–2269) 1883 (1522–2236) 1853 (1482–2227) 0.60
  Total fiber (g/day)b, median (IQR) 13.3 (10.4–17.0) 12.7 (10.0–16.5) 12.9 (9.6–17.0) 12.8 (10.0–16.4) 0.80
  Total meat (g/day)b, median (IQR) 44.1 (29.0–69.6) 43.2 (28.6–67.0) 41.6 (25.0–61.2) 46.0 (28.2–71.7) 0.47
  CRP (mg/L), median (IQR) 0.1 (0.08–0.1) 0.3 (0.2–0.3) 0.5 (0.4–0.6) 1.2 (0.9–1.8) <0.0001
Categorical variables
  Smoking, n (%) 0.24
  Current smoker 13 (7.9) 17 (10.8) 16 (9.5) 23 (13.9)
  Past smoker 52 (31.7) 59 (37.3) 69 (40.8) 64 (38.6)
  Never smoker 99 (60.4) 82 (51.9) 84 (49.7) 79 (47.6)
  Drinking, n (%) 0.89
  Current drinker 118 (72.0) 114 (72.2) 117 (69.2) 118 (71.1)
  Past drinker 4 (2.4) 8 (5.1) 6 (3.6) 6 (3.6)
  Never drinker 42 (25.6) 36 (22.8) 46 (27.2) 42 (25.3)
  Family CRC history, n (%) 20 (12.2) 21 (13.3) 21 (12.4) 17 (10.2) 0.86
  Diabetes Mellitus, n (%) 11 (6.7) 9 (5.7) 8 (4.7) 12 (7.2) 0.78

an, number of subjects; BMI, body mass index; METs, metabolic equivalents; CRC, colorectal cancer; SD, standard deviation; IQR, inter-quartile range.

bEnergy-adjusted.