Table1.
Patient clinicopathologic characteristics, stratified by ABO blood type.
| Variable, no (%) | Over cohort | Blood group | P-value | Blood group | P-value | ||||
|---|---|---|---|---|---|---|---|---|---|
| O | A | B | AB | O | Non-O | ||||
| Total case | 691 | 262 (37.9) | 199 (28.8) | 165 (23.9) | 65 (9.4) | 262 (37.9) | 429 (62.1) | ||
| Age (years) | 0.882 | 0.525 | |||||||
| <45 | 187 (27.1) | 65 (24.8) | 58 (29.1) | 46 (27.9) | 18 (27.7) | 65 (24.8) | 122 (28.4) | ||
| 45–60 | 308 (44.6) | 118 (45.0) | 83 (41.7) | 77 (46.7) | 30 (46.2) | 118 (45.0) | 190 (44.3) | ||
| >60 | 196 (28.4) | 79 (30.2) | 58 (29.1) | 42 (25.5) | 17 (26.2) | 79 (30.2) | 117 (27.3) | ||
| Sex | 0.982 | 0.709 | |||||||
| Male | 564 (81.6) | 212 (80.9) | 163 (81.9) | 136 (82.4) | 53 (81.5) | 212 (80.9) | 352 (82.1) | ||
| Female | 127 (18.4) | 50 (19.1) | 36 (18.1) | 29 (17.6) | 12 (18.5) | 50 (19.1) | 77 (17.9) | ||
| Place of residence | 0.378 | 0.085 | |||||||
| Rural | 356 (51.5) | 124 (47.3) | 109 (54.8) | 89 (53.9) | 34 (52.3) | 124(47.3) | 232 (54.1) | ||
| Urban | 335 (48.5) | 138 (52.7) | 90 (45.2) | 76 (46.1) | 31 (47.7) | 138 (52.7) | 197 (45.9) | ||
| Child-Pugh stage | 0.209 | 0.127 | |||||||
| A | 648 (93.8) | 241 (92.0) | 192 (96.5) | 153 (92.7) | 62 (95.4) | 241 (92.0) | 407 (94.9) | ||
| B | 43 (6.2) | 21 (8.0) | 7 (3.5) | 12 (7.3) | 3 (4.6) | 21 (8.0) | 22 (5.1) | ||
| Smoking | 0.320 | 0.973 | |||||||
| No | 308 (44.6) | 117 (46.0) | 79 (39.7) | 80 (48.5) | 32 (49.2) | 117 (46.0) | 191 (44.5) | ||
| Yes (former/current) | 383 (55.4) | 145 (55.3) | 120 (60.3) | 85 (51.5) | 33 (50.8) | 145 (55.3) | 238 (55.4) | ||
| Alcohol consumption | 0.087 | 0.936 | |||||||
| No | 236 (34.2) | 89 (34.0) | 58 (29.1) | 59 (35.8) | 30 (46.2) | 89 (34.0) | 147 (34.3) | ||
| Yes (former/current) | 455 (65.8) | 173 (66.0) | 141 (70.9) | 106 (64.2) | 35 (53.8) | 173 (66.0) | 282 (65.7) | ||
| Hepatitis status | 0.954 | 0.414 | |||||||
| HBV | 538 (77.9) | 197 (75.2) | 159 (79.9) | 130 (78.8) | 52 (80.0) | 197 (75.2) | 341 (79.5) | ||
| HCV | 51 (7.4) | 20 (7.6) | 15 (7.5) | 12 (7.3) | 4 (6.2) | 20 (7.6) | 31 (7.2) | ||
| HBV + HCV | 7 (1.0) | 2 (0.8) | 2 (1.0) | 2 (1.2) | 1 (1.5) | 2 (0.8) | 5 (1.2) | ||
| None | 95 (13.7) | 43 (16.4) | 23 (11.6) | 21 (12.7) | 8 (12.3) | 43 (16.4) | 52 (12.1) | ||
| Serum AFP level | 0.014 | 0.003 | |||||||
| <400 ng/ml | 409 (59.2) | 174 (66.4) | 106 (53.3) | 89 (53.9) | 40 (61.5) | 174 (66.4) | 235 (54.8) | ||
| >400 ng/ml | 282 (40.8) | 88 (33.6) | 93 (46.7) | 76 (46.1) | 25 (38.5) | 88 (33.6) | 194 (45.2) | ||
| Tumor differentiation | 0.881 | 0.936 | |||||||
| Well | 118 (17.0) | 43 (16.4) | 38 (19.1) | 28 (17.0) | 9 (13.8) | 43 (16.4) | 75 (17.5) | ||
| Moderate | 413 (59.8) | 158 (60.3) | 117 (58.8) | 101 (61.2) | 37 (56.9) | 158 (60.3) | 255 (59.4) | ||
| Poor | 160 (23.2) | 61 (23.3) | 44 (22.1) | 36 (21.8) | 19 (29.3) | 61 (23.3) | 99 (23.1) | ||
| Liver cirrhosis | 0.846 | 0.719 | |||||||
| No | 191 (27.7) | 76 (29.0) | 56 (28.2) | 41 (24.8) | 18 (27.7) | 76 (29.0) | 115 (26.8) | ||
| Yes | 481 (69.6) | 180 (68.7) | 139 (69.8) | 117 (71.0) | 45 (69.2) | 180 (68.7) | 301 (70.2) | ||
| Unknown | 19 (2.7) | 6 (2.3) | 4 (2.0) | 7 (4.2) | 2 (3.1) | 6 (2.3) | 13 (3.0) | ||
| Tumor size | 0.428 | 0.367 | |||||||
| ≤5 cm | 362 (52.4) | 143 (54.6) | 95 (47.7) | 87 (52.7) | 37 (56.9) | 143 (54.6) | 219 (51.0) | ||
| >5 cm | 329 (47.6) | 119 (45.4) | 104 (52.3) | 78 (47.3) | 28 (43.1) | 119 (45.4) | 210 (49.0) | ||
| AJCC TNM Stage | 0.678 | 0.643 | |||||||
| I | 181 (26.2) | 72 (27.5) | 50 (25.1) | 45 (27.3) | 14 (21.5) | 72 (27.5) | 109 (25.4) | ||
| II | 287 (41.5) | 103 (39.3) | 79 (39.7) | 74 (44.8) | 31 (47.7) | 103 (39.3) | 184 (42.9) | ||
| III | 223 (32.3) | 87 (33.2) | 70 (35.2) | 46 (27.9) | 20 (30.8) | 87 (33.2) | 136 (31.7) | ||
Notes: AFP α-fetoprotein; HBV hepatitis B virus; HCV hepatitis C virus; TNM Tumor node metastasis.